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Name Beta 2 Microglobulin ELISA kit
Price $359.00
Category Name
Test96
MethodELISA: Enzyme Linked Immunosorbent Assay
PrincipleSandwich Complex
Detection Range0-20 ug/ml
Sample20 ul serum
Specificity93%
Sensitivity0.1 ug/mL
Total Time~ 80 min
Shelf Life12-14 Months from the manufacturing date

Item #:                    4200-18   Quantity:               

 
   




 Description


β2-Microglobulin ELISA Test kit





β2-MG ELISA Test kit Intended Use
β2-Microglobulin ELISA test kit is intended for the quantitative determination of β2-microglobulin in human serum. The result of this assay may be used use as an aid in the diagnosis of kidney disease.





β2-Microglobulin ELISA Kit Components:
• Microplate: 96 wells coated with murine monoclonal anti-β-2MG
• HRP Conjugated sheep anti-β2-MG
• Reference Standard Set
• Serum Diluent
• TMB
• Stop Solution (1N HCL)





Method Principle
This Diagnostic Automation/ Cortez Diagnostics Inc. Human β2-MG ELISA test is based on the principle of a solid phase enzyme-linked immunosorbent assay (ELISA) providing a sensitive and reliable assay for the measurement of β2-microglobulin in human serum. This assay system utilizes a monoclonal anti-β2-MG antibody for solid phase immobilization on the microplate wells. For further details please refer to complete instructions manual supplied with the product.





Background Information
Beta-2-microglobulin (β2-MG) is a low molecular weight protein which is expressed by the nucleated cells of the body and in many tumor lines. Typically only trace amounts of β2-MG are excreted in the urine and higher rates are interpreted as evidence of tubular dysfunction. Urinary excretion is markedly increased in tubulointerstitial disorders, and where aminoglycosides and anti-inflammatory compounds are present. β2-MG is also excreted in increased amounts in the urine of patients with upper urinary tract infections and connective-tissue diseases such as rheumatoid arthritis and Sjogren’s syndrome. Elevated serum concentrations in the presence of normal glomerular filtration rate suggest increased β2-MG production or release. In patients with rheumatoid arthritis, systemic lupus erythematosus, sarcoidosis and some viral diseases including cytomegalovirus, non-A and non-B hepatitis and infectious mononucleosis, the β2-MG serum level changes in relation to disease activity.




For more information about ELISA Kits, Rapid Tests, IFA Kits, CLIA Test Kits, or Serology tests, please see our website home page, or contact our Customer Service Representative at 818-591-3030.