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Name Troponin I Rapid Test Serum-WB (Cassette) (Min. order:200 Tests) Not for OTC use
Price $163.00
Category NameDrug Tests
TestBoxed in 25 tests

Item #:                    166772-1-19   Quantity:               

 
   




 Description


The Cortez Diagnostic Inc. TnI Rapid Test is an immunochromatography based one step in vitro test. It is designed for qualitative determination of cardiac troponin I (cTnI) in human serum, whole blood or plasma specimens as an aid in the diagnosis of myocardial infarction.

Cardiac troponin I (cTnI) is a cardiac muscle protein with a molecular weight of 22.5 kilodaltons. Together with troponin T (TnT) and troponin C (TnC), TnI forms a troponin complex in heart to play a fundamental role in the transmission of intracellular calcium signal actin-myosin interaction. The human cTnI has an additional amino acid residues on its N-terminal that are not exist on the skeletal forms thus making cTnI a specific marker for indicating cardiac infarction. cTnI is released rapidly into blood after the onset of acute myocardial infarction (AMI). Its release pattern is similar to CK-MB (4-6 hours after the onset of AMI). However, CK-MB level returns to normal after 36-48 hours, while levels of cTnI remains elevated for up to 6-10 days. The level of cTnI is very low in normal healthy people, and not detected in patients with skeletal muscle injury. Therefore, cTnI is a specific marker for diagnosis of AMI.
Cortez Troponin I Rapid Test is a sandwich immunoassay. When sample is added to sample pad, it moves through the conjugate pad and mobilizes gold anti-cTnI conjugate that is coated on the conjugate pad. The mixture moves along the membrane by capillary action and reacts with anti-cTnI antibody that is coated on the test region. If cTnI is present at levels of 0.11 ng/mL(Bayer ACS: 180) or 1.5 ng/mL(Abbott AxSYM)or greater*, the result is the formation of a colored band in the test region. If there is no cTnI in the sample, the area will remain colorless. The sample continues to move to the control area and forms a pink to purple color, indicating the test is working and the result is valid.