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Name Varicella-Zoster IgM ELISA kit
Price $228.00
Category NameInfectious Disease ELISA kits
Test96
MethodELISA: Enzyme Linked Immunosorbent Assay
PrincipleELISA - Antigen Coated Plate
Detection RangeQualitative - Positive, Negative Control
Sample10ul
Specificity100%
Sensitivity100%
Total Time~ 50 min
Shelf Life12 Months from the manufacturing date

Item #:                    1413-1   Quantity:               

 
   




 Description


VZV ELISA Test kit




VZV ELISA Test kit Intended Use
Varicella-Zoster Virus (VZV) IgM ELISA is intended for the detection of IgM antibody to Varicella-Zoster virus in human serum as an aid in the diagnosis of primary infection or reactivation.




VZV IgM ELISA Kit Components:
• Microplate: 96 wells alternating strips coated with inactivated & control antigen
• HPR-Enzyme Conjugate Goat anti-human IgM
• Absorbent Solution: goat/sheep antihuman IgG
• Sample Diluent Type II
• Calibrator
• Positive Control
• Negative Control
• Chromogen/Substrate Solution Type I
• Wash Buffer Type I (20X)
• Stop Solution (1N H2SO4)




Method Principle
This Diagnostic Automation/ Cortez Diagnostics Inc. Human VZV IgM ELISA test system is designed to detect IgM class antibodies to VZV antigen in human sera. When antigens bound to the microplate wells are brought into contact with a patient serum, antigen specific antibody, if present, will bind to the antigen on the solid phase forming antigen-antibody complexes. For further details please refer to complete instructions manual supplied with the product.




Background Information
Varicella, more commonly known as chickenpox and herpes zoster are known clinical manifestations of infection with varicella-zoster virus (VZV); highly contagious disease characterized by widely spread vesicular eruptions and fever. The disease is endemic in the U.S. and most commonly affects children from five to eight years of age, although adults and younger children, including infants, may develop chickenpox. Every two to five years, usually in the winter or spring, the number of cases increases to epidemic levels. VZV infection during early pregnancy has been implicated in congenital anomalies in rare cases. Herpes zoster is mainly a disease of adults, with most cases appearing in patients fifty years or older. Evidence suggests that this manifestation of VZV infections results from a reactivation of virus which has remained latent in the sensory spinal ganglia after the primary infection rather than a reintroduction of the virus into the host. ELISA methodology is a sensitive and specific method for the detection of VZV antibody in human sera.



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